2C-B

Product Beschrijving

2C-B (4-Bromo-2,5-dimethoxyphenethylamine) is a core structural analog within the 2C family of substituted phenethylamines, characterized by methoxy groups at positions 2 and 5 and a bromine atom at position 4 of the benzene ring. In scientific and forensic environments, standardized 24 mg pressed matrices serve as calibrated benchmarks for toxicological screening, chromatographic separation studies, and qualitative detection of illicit substituted phenethylamines.

Chemical & Pharmacodynamic Properties

• Chemical Formula & Weight: $\text{C}_{10}\text{H}_{14}\text{BrNO}_2 \cdot \text{HCl}$ | 296.59 g/mol (HCl salt)

• Receptor Affinity & Target Profile: Acts primarily as a partial agonist with high binding affinity at central serotonin $5\text{-HT}_{2\text{A}}$, $5\text{-HT}_{2\text{B}}$, En $5\text{-HT}_{2\text{C}}$ receptor subtypes, alongside moderate modulatory action at alpha-adrenergic receptors and trace amine-associated receptors (TAAR1).

• Analytical Matrix Integrity: Standardized solid compressed matrix designed to test degradation curves, binding kinetics, and solvent solubility in quantitative liquid chromatography-mass spectrometry ($\text{LC-MS}$) and gas chromatography-mass spectrometry ($\text{GC-MS}$) workflows.

• Presumptive Assay Validation: Serves as a control substance to evaluate colorimetric reaction specificity against common presumptive testing reagents (Marquis, Mecke, Mandelin, and Froehde).

Forensic Safety & Legal Governance

• Strict Laboratory Application: Intended exclusively for licensed forensic facilities, diagnostic reference laboratories, and accredited chemical research centers.

• Toxicity Profile: Inadvertent systemic exposure in humans presents acute clinical risks, including sympathomimetic toxicity (marked tachycardia, hypertension, hyperthermia), peripheral vasoconstriction, severe sensory distortion, and acute neuropsychiatric distress.

• Controlled Substance Status: 2C-B is classified as a Schedule I controlled substance in the United States under the Controlled Substances Act, a Class A drug in the United Kingdom, and an internationally controlled compound under Schedule II of the UN Convention on Psychotropic Substances. Acquisition, handling, and disposal require strict institutional licensing and regulatory documentation.

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